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Taxol and various Cures
Vancouver SW Washington
741 Posts
December 31, 2022 - 4:09 pm

Taxol is the medicinal name of the product of evergreen yew and now (circa 2007) deciduous hazelnut trees. The taxol is produced in the wood by tree symbiotic endophytes. Taxol as a medicine is something I'm not interested in right now. Taxol for it's role and function mechanism as a medicine to the tree itself is the thing that interests me.

This is to say that I would like to learn how to transfer the specific endophytes from the hazelnut wood and inocculate my existing large turkish hazel tree, then from the existing tree to new native seedlings.

Once -if ever the time arrives and I can be in control of young hazlenut trees of this symbiotic nature, then -I would cultivate on a one-per-one, root-near-root, diseased prunus (stone fruits) nearby. There is something like this on the table already and aimed at taxol production for human cancer, so in other words it's not kind of locked into big company pharma-top-secret shelves. So the proof of concept (ie. per italics para-2) exists as part of it online: disclosed circa 2018 , a few years one way or the other, nature dot com and footnotes

Does anyone have any helping information or experience on the above italics portion of what I'm attempting?

Of possible value to the community is my observations in Wintler Park link and proofs of production, but not shown in the link is at least a 30 year old native hazelnut growing within 6 feet -in which I assume is the medicine supplier;

Annual observations apricot pair as planted in Nature

John S
2736 Posts
December 31, 2022 - 8:21 pm

What I have been told is that you take some of the soil from beneath a mature one of those plants and put the soil beneath your plants and the mycorrhizae should transfer.   I do have both a mature yew and a mature hazelnut/filbert in case you are interested.

John S

Vancouver SW Washington
741 Posts
December 31, 2022 - 10:32 pm

What if any comments would you have after findings in the various figures in my first link that endophytes vary in the kinds presented in woody material verses the root are? The figures are actually had by invoking the only link in the page I aimed at. Here are two;

...and all these 18 endophyte types applies to hazelnut, but just remember they to me appear to be unique (ie. no underground endophytes exist above ground).

I thought somebody would have said wood to wood transfer would be the most efficient, but of course I wasn't sure. Can you itemize your answer a bit more?

John S
2736 Posts
January 1, 2023 - 12:38 pm

I'm not sure what itemizing would mean here.  The Filbert is about 12 feet tall. Maybe 10 years old. Planted by squirrels. 

I planted the yew from a cutting and it is probably about 12 years old. 7 feet tall and wide.

John S

Vancouver SW Washington
741 Posts
January 1, 2023 - 6:34 pm

I meant pick an online science principle or item (itemize) that will support my goal of transferring these endophytes capable of produceing the Taxol. I have no experience dealing in mycorrhizae let alone where to get the strains specifically mentioned. 

Endophyte in the wood of such trees as hazelnut prevents wood rot via the endophyte itself or by the Taxol it produces, or both. This truth comes posted via a previous 2019 topic still listed with DanielW, You, and Me in it. [ie. trees-fight-infections ]

I have oldest native hazelnut trees on our side (wintler Park site), but thanks though. The good news is I won't need my Turkish Tree hazel because I found a Washington seller of young native hazelnut trees for $6.25 a piece through Burntridge Nursery. Both the endophyte rich scion and rootstock together is much faster (my opinion) then the transferring soil idea I think you thought would work.

Hopefully this will get my zero producing Lydecker plums producing natural like the Wintler apricot seedling has become. (fingers crossed)

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